详情描述
Note: Tapentadol HCl is discontinued | Tapentadol is a centrally acting opioid analgesic of the benzenoid class with a dual mode of action as an agonist of the μ-opioid receptor and as a norepinephrine reuptake inhibitor (NRI).[3] Its analgesic properties come into effect within thirty-two minutes of oral administration, and last for 4–6 hours. This agent may be effective in the management of pain, cancer-related and other.
Product information
CAS Number: 175591-09-0
Molecular Weight: 257.80
Formula: C14H24ClNO
Synonym:
CG-5503
Nucynta
Palexia
Tapal
Chemical Name: 3-[(2R,3R)-1-(dimethylamino)-2-methylpentan-3-yl]phenol hydrochloride
Smiles: Cl.C[C@@H](CN(C)C)[C@@H](CC)C1C=C(O)C=CC=1
InChiKey: ZELFLGGRLLOERW-YECZQDJWSA-N
InChi: InChI=1S/C14H23NO.ClH/c1-5-14(11(2)10-15(3)4)12-7-6-8-13(16)9-12;/h6-9,11,14,16H,5,10H2,1-4H3;1H/t11-,14+;/m0./s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: Soluble in DMSO
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- Schwartz S, Etropolski M, Shapiro DY, Okamoto A, Lange R, Haeussler J, Rauschkolb C. Safety and efficacy of tapentadol ER in patients with painful diabetic peripheral neuropathy: results of a randomized-withdrawal, placebo-controlled trial. Curr Med Res Opin. 2011 Jan;27(1):151-62.
Products are for research use only. Not for human use.