详情描述
Pentamidine dihydrochloride (MP-601205 dihydrochloride) is an antimicrobial agent and interferes with DNA biosynthetics. Pentamidine dihydrochloride inhibits parasite Leishmania infantum with an IC50 of 2.5 μM. Pentamidine dihydrochloride is a potent and selective protein tyrosine phosphatases (PTPases) and phosphatase of regenerating liver (PRL) inhibitor. Pentamidine dihydrochloride has the potential for Gambian trypanosomiasis, antimony-resistant leishmaniasis, and Pneumocystis carinii pneumonia treatment. Antitumor and antibacterial activities.
Product information
CAS Number: 50357-45-4
Molecular Weight: 413.34
Formula: C19H26Cl2N4O2
Synonym:
MP601205 dihydrochloride
MP 601205 dihydrochloride
MP-601205 dihydrochloride
Chemical Name: 4-{[5-(4-carbamimidoylphenoxy)pentyl]oxy}benzene-1-carboximidamide dihydrochloride
Smiles: Cl.Cl.NC(=N)C1C=CC(=CC=1)OCCCCCOC1C=CC(=CC=1)C(N)=N
InChiKey: HWURPQUPKQFGJI-UHFFFAOYSA-N
InChi: InChI=1S/C19H24N4O2.2ClH/c20-18(21)14-4-8-16(9-5-14)24-12-2-1-3-13-25-17-10-6-15(7-11-17)19(22)23;;/h4-11H,1-3,12-13H2,(H3,20,21)(H3,22,23);2*1H
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.