详情描述
Tamoxifen is a selective estrogen receptor modulator (SERM) and antagonist of ER action in breast tissue and breast cancer cells. It is reported to be effective in the treatment of early breast cancer to prevent tumor growth. Importantly, tamoxifen has been reported to act as an ER agonist in bone and blood vessels, helping to minimize osteoporosis and reduce the risk of cardiovascular disease in post-menopausal women. Also, tamoxifen is a partial ER agonist in uterine tissues and is reported to increase the risk of endometrial carcinoma.
Product information
CAS Number: 10540-29-1
Molecular Weight: 371.51
Formula: C26H29NO
Synonym:
Mammaton
Novaldex
ICI47699
Z-Tamoxifen
trans-Tamoxifen
Chemical Name: (2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethyl)dimethylamine
Smiles: CC/C(=C(\C1C=CC=CC=1)/C1C=CC(=CC=1)OCCN(C)C)/C1C=CC=CC=1
InChiKey: NKANXQFJJICGDU-QPLCGJKRSA-N
InChi: InChI=1S/C26H29NO/c1-4-25(21-11-7-5-8-12-21)26(22-13-9-6-10-14-22)23-15-17-24(18-16-23)28-20-19-27(2)3/h5-18H,4,19-20H2,1-3H3/b26-25-
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.