详情描述
PEAQX, also known as NVP-AAM077; is a competitive antagonist at the NMDA receptor. Although originally described as 100-fold selective for GluN1/GluN2A receptors vs. GluN1/GluN2B receptors, more detailed studies of the Ki of PEAQX revealed it only shows a 5 fold difference in affinity for GluN1/GluN2A vs. GluN1/GluN2B receptors. It is also a potent anticonvulsant in animal tests.
Product information
CAS Number: 2102348-87-6
Molecular Weight: 560.15
Formula: C17H15BrN3Na4O6P
Synonym:
NVP-AAM077 tetrasodium hydrate
NVP-AAM 077 tetrasodium hydrate
Chemical Name: tetrasodium 5-({[(1S)-1-(4-bromophenyl)ethyl]amino}(phosphonato)methyl)quinoxaline-2, 3-bis(olate) hydrate
Smiles: O.[Na+].[Na+].[Na+].[Na+].C[C@H](NC(C1=CC=CC2=NC([O-])=C([O-])N=C21)P([O-])([O-])=O)C1=CC=C(Br)C=C1
InChiKey: SMGAGBKXHAHCGQ-VSYRWHDMSA-J
InChi: InChI=1S/C17H17BrN3O5P.4Na.H2O/c1-9(10-5-7-11(18)8-6-10)19-17(27(24,25)26)12-3-2-4-13-14(12)21-16(23)15(22)20-13;;;;;/h2-9,17,19H,1H3,(H,20,22)(H,21,23)(H2,24,25,26);;;;;1H2/q;4*+1;/p-4/t9-,17?;;;;;/m0...../s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.