详情描述
Triamterene-d5 is intended for use as an internal standard for the quantification of triamterene by GC- or LC-MS. Triamterene is an inhibitor of the epithelial sodium channel (ENaC; IC50 = 4.5 µM for the rat channel). In vivo, triamterene (0.5-32 mg/animal) enhances sodium secretion and decreases potassium secretion in adrenalectomized rats.2 Formulations containing triamterene have been used in the treatment of edema.
Product information
CAS Number: 1189922-23-3
Molecular Weight: 258.29
Formula: C12H11N7
Synonym:
Dyrenium D5
Chemical Name: 6-[(2,3,4,5,6-²H₅)phenyl]pteridine-2,4,7-triamine
Smiles: [2H]C1=C(C2=NC3=C(N=C2N)N=C(N)N=C3N)C([2H])=C([2H])C([2H])=C1[2H]
InChiKey: FNYLWPVRPXGIIP-RALIUCGRSA-N
InChi: InChI=1S/C12H11N7/c13-9-7(6-4-2-1-3-5-6)16-8-10(14)18-12(15)19-11(8)17-9/h1-5H,(H6,13,14,15,17,18,19)/i1D,2D,3D,4D,5D
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.