Pitavastatin D4

Pitavastatin D4 (NK-104 D4) is deuterium labeled Pitavastatin. Pitavastatin is a potent HMG-CoA reductase inhibitor.

Product information

CAS Number: 2070009-71-9

Molecular Weight: 425.49

Formula: C25H24FNO4

Synonym:

NK-104 D4

Chemical Name: (3R, 5S, 6E)-7-{2-cyclopropyl-4-[4-fluoro(2, 3, 5, 6-H)phenyl]quinolin-3-yl}-3, 5-dihydroxyhept-6-enoic acid

Smiles: [2H]C1=C(C2=C(/C=C/[C@@H](O)C[C@@H](O)CC(O)=O)C(=NC3=CC=CC=C32)C2CC2)C([2H])=C([2H])C(F)=C1[2H]

InChiKey: VGYFMXBACGZSIL-FZVTUHSMSA-N

InChi: InChI=1S/C25H24FNO4/c26-17-9-7-15(8-10-17)24-20-3-1-2-4-22(20)27-25(16-5-6-16)21(24)12-11-18(28)13-19(29)14-23(30)31/h1-4,7-12,16,18-19,28-29H,5-6,13-14H2,(H,30,31)/b12-11+/t18-,19-/m1/s1/i7D,8D,9D,10D

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: To be determined

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Imanishi T, Ikejima H, Tsujioka H, Kuroi A, Kobayashi K, Shiomi M, Muragaki Y, Mochizuki S, Goto M, Yoshida K, Akasaka T. Combined effects of an 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor and angiotensin II receptor antagonist on nitric oxide bioavailability and atherosclerotic change in myocardial infarction-prone Watanabe heritable hyperlipidemic rabbits. Hypertens Res. 2008 Jun;31(6):1199-208.

Products are for research use only. Not for human use.