详情描述
Salicin is a natural COX inhibitor.
Product information
CAS Number: 138-52-3
Molecular Weight: 286.28
Formula: C13H18O7
Synonym:
NSC 5751
NSC-5751
NSC5751
Chemical Name: (2R, 3S, 4S, 5R, 6S)-2-(hydroxymethyl)-6-[2-(hydroxymethyl)phenoxy]oxane-3, 4, 5-triol
Smiles: O[C@@H]1[C@@H](O)[C@@H](O[C@H](CO)[C@H]1O)OC1=CC=CC=C1CO
InChiKey: NGFMICBWJRZIBI-UJPOAAIJSA-N
InChi: InChI=1S/C13H18O7/c14-5-7-3-1-2-4-8(7)19-13-12(18)11(17)10(16)9(6-15)20-13/h1-4,9-18H,5-6H2/t9-,10-,11+,12-,13-/m1/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO: 57 mg/mL(199.1 mM). Water: 24 mg/mL(83.83 mM).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
Salicin (Salicoside, Salicine) is a phenol β-glycosid produced from willow bark that shows anti-inflammatory effects. Salicin is a prodrug which is gradually transported to the lower part of the intestine, hydrolyzed to saligenin by intestinal bacteria, and converted to salicylic acid after absorption. It thus produces an antipyretic action without causing gastric injury.
References:
- Jun Yan He, et al. Columbia Research SCholars Journal, 2016.
- Akao T, et al. Planta Med, 2002, 68(8), 714-718.
- Maclagan T, et al. Br Med J, 1876, 1(803), 627.
Products are for research use only. Not for human use.