ICA 110381

ICA 110381 is a KV7.2/7.3 activator with EC50 of 0.38 μM.

Product information

CAS Number: 325457-99-6

Molecular Weight: 267.11

Formula: C12H8Cl2N2O

Chemical Name: 4-chloro-N-(6-chloropyridin-3-yl)benzamide

Smiles: O=C(NC1=CN=C(Cl)C=C1)C1C=CC(Cl)=CC=1

InChiKey: FOYOGIUAMYSVIT-UHFFFAOYSA-N

InChi: InChI=1S/C12H8Cl2N2O/c13-9-3-1-8(2-4-9)12(17)16-10-5-6-11(14)15-7-10/h1-7H,(H,16,17)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO: 53 mg/mL(198.42 mM).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Amato G, et al. N-Pyridyl and Pyrimidine Benzamides as KCNQ2/Q3 Potassium Channel Openers for the Treatment of Epilepsy. ACS Med Chem Lett. 2011 Mar 31;2(6):481-4.

Products are for research use only. Not for human use.