RO5203648 hydrochloride

RO5203648 hydrochloride is a partial agonist of Trace amine-associated receptor 1 (TAAR1).

Product information

CAS Number: 1043491-54-8

Molecular Weight: 231.08

Formula: C9H8Cl2N2O

Chemical Name: (4S)-4-(3, 4-dichlorophenyl)-4, 5-dihydro-1, 3-oxazol-2-amine

Smiles: NC1=NC(CO1)C1=CC(Cl)=C(Cl)C=C1

InChiKey: HGGPGNSCBBAGJN-UHFFFAOYSA-N

InChi: InChI=1S/C9H8Cl2N2O/c10-6-2-1-5(3-7(6)11)8-4-14-9(12)13-8/h1-3,8H,4H2,(H2,12,13)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO, not in water

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Pei Y, Mortas P, Hoener MC, Canales JJ. Selective activation of the trace amine-associated receptor 1 decreases cocaine's reinforcing efficacy and prevents cocaine-induced changes in brain reward thresholds. Prog Neuropsychopharmacol Biol Psychiatry. 2015 Dec 3;63:70-5.
2. Cotter R, Pei Y, Mus L, Harmeier A, Gainetdinov RR, Hoener MC, Canales JJ. The trace amine-associated receptor 1 modulates methamphetamine's neurochemical and behavioral effects. Front Neurosci. 2015 Feb 13;9:39.

Products are for research use only. Not for human use.