NADPH tetrasodium salt

NADPH tetrasodium salt is a cofactor, used to donate electrons and a hydrogens to reactions catalyzed by some enzymes.

Product information

CAS Number: 2646-71-1

Molecular Weight: 833.35

Formula: C21H26N7Na4O17P3

Chemical Name: [(2R, 3S, 4R, 5R)-5-(3-carbamoyl-1, 4-dihydropyridin-1-yl)-3, 4-dihydroxyoxolan-2-yl]methyl sodium [({[(2R, 3R, 4R, 5R)-5-(6-amino-9H-purin-9-yl)-4-{[bis(sodiooxy)phosphoryl]oxy}-3-hydroxyoxolan-2-yl]methoxy}(sodiooxy)phosphoryl)oxy]phosphonate

Smiles: NC(=O)C1CC=CN(C=1)[C@@H]1O[C@H](COP(=O)(OP(=O)(OC[C@H]2O[C@H]([C@H](OP(=O)(O[Na])O[Na])[C@@H]2O)N2C=NC3=C2N=CN=C3N)O[Na])O[Na])[C@@H](O)[C@H]1O

InChiKey: WYWWVJHQDVCHKF-ITGWJZMWSA-J

InChi: InChI=1S/C21H30N7O17P3.4Na/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(44-46(33,34)35)14(30)11(43-21)6-41-48(38,39)45-47(36,37)40-5-10-13(29)15(31)20(42-10)27-3-1-2-9(4-27)18(23)32;;;;/h1,3-4,7-8,10-11,13-16,20-21,29-31H,2,5-6H2,(H2,23,32)(H,36,37)(H,38,39)(H2,22,24,25)(H2,33,34,35);;;;/q;4*+1/p-4/t10-,11-,13-,14-,15-,16-,20-,21-;;;;/m1..../s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: H2O : ≥ 35 mg/mL (42.00 mM)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Ye Y, Guo X, He X, Zhang M, He H, Qiu D, Guo Z. High-resolution mass spectrometry-based approach for the identification and profiling of the metabolites of taletrectinib formed in liver microsomes. Drug Test Anal. 2021 Feb 1. doi: 10.1002/dta.3008. Epub ahead of print. PMID: 33527739.
2. Su J, Jia F, Lu J, Chen W, Sun H, Liu T, Wu X. Characterization of the metabolites of rosmarinic acid in human liver microsomes using liquid chromatography combined with electrospray ionization tandem mass spectrometry. Biomed Chromatogr. 2020 Apr;34(4):e4806. doi: 10.1002/bmc.4806. Epub 2020 Feb 13. PMID: 32012312.

Products are for research use only. Not for human use.