详情描述
Ethoxysanguinarine is a benzophenanthridine alkaloid natural product that is mainly found in Macleaya cordata. Ethoxysanguinarine inhibits viability and induces apoptosis of colorectal cancer cells by inhibiting protein phosphatase 2A (CIP2A).
Product information
CAS Number: 28342-31-6
Molecular Weight: 377.39
Formula: C22H19NO5
Chemical Name: 23-ethoxy-24-methyl-5, 7, 18, 20-tetraoxa-24-azahexacyclo[11.11.0.0, .0, .0, .0, ]tetracosa-1(13), 2, 4(8), 9, 11, 14(22), 15, 17(21)-octaene
Smiles: CCOC1C2=C3OCOC3=CC=C2C2=CC=C3C=C4OCOC4=CC3=C2N1C
InChiKey: FCEXWTOTHXCQCQ-UHFFFAOYSA-N
InChi: InChI=1S/C22H19NO5/c1-3-24-22-19-13(6-7-16-21(19)28-11-25-16)14-5-4-12-8-17-18(27-10-26-17)9-15(12)20(14)23(22)2/h4-9,22H,3,10-11H2,1-2H3
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 60 mg/mL (158.99 mM; Need ultrasonic) H2O : < 0.1 mg/mL (insoluble)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥360 days if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- Jin L, et al. Ethoxysanguinarine inhibits viability and induces apoptosis of colorectal cancer cells by inhibiting CIP2A. Int J Oncol. 2018 Mar 16.
Products are for research use only. Not for human use.