Catalog No. Size 价格库存数量
S0786-2 2mg solid ¥145
S0786-10 10mg solid ¥435


Liensinine is an autophagy/mitophagy inhibitor. Liensinine, a major isoquinoline alkaloid, extracted from the seed embryo of Nelumbo nucifera Gaertn, has a wide range of biological activities, including anti-arrhythmias, anti-hypertension, anti-pulmonary fibrosis, relaxation on vascular smooth muscle, etc.

Product information

CAS Number: 2586-96-1

Molecular Weight: 610.74

Formula: C37H42N2O6

Chemical Name: 4-{[(1R)-6, 7-dimethoxy-2-methyl-1, 2, 3, 4-tetrahydroisoquinolin-1-yl]methyl}-2-{[(1R)-1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-1, 2, 3, 4-tetrahydroisoquinolin-7-yl]oxy}phenol

Smiles: CN1CCC2=CC(OC)=C(C=C2[C@H]1CC1=CC(OC2=CC3[C@@H](CC4C=CC(O)=CC=4)N(C)CCC=3C=C2OC)=C(O)C=C1)OC


InChi: InChI=1S/C37H42N2O6/c1-38-14-13-26-20-35(43-4)37(22-29(26)30(38)16-23-6-9-27(40)10-7-23)45-33-18-24(8-11-32(33)41)17-31-28-21-36(44-5)34(42-3)19-25(28)12-15-39(31)2/h6-11,18-22,30-31,40-41H,12-17H2,1-5H3/t30-,31-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 50 mg/mL (81.87 mM; Need ultrasonic)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200


  1. Zhou J, et al. A novel autophagy/mitophagy inhibitor liensinine sensitizes breast cancer cells to chemotherapy through DNM1L-mediated mitochondrial fission. Autophagy. 2015;11(8):1259-79.

Products are for research use only. Not for human use.


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