p38 MAPK-IN-2

p38 MAPK-IN-2 is an inhibitor of p38 kinase.

Product information

CAS Number: 635725-16-5

Molecular Weight: 415.85

Formula: C20H19ClFN5O2

Chemical Name: 1-{4-[5-(4-chloro-2-fluorophenyl)-4-(pyrimidin-4-yl)-1H-pyrazol-3-yl]piperidin-1-yl}-2-hydroxyethan-1-one

Smiles: OCC(=O)N1CCC(CC1)C1=NNC(=C1C1=CC=NC=N1)C1=CC=C(Cl)C=C1F

InChiKey: IGGNAIYXGIUMQZ-UHFFFAOYSA-N

InChi: InChI=1S/C20H19ClFN5O2/c21-13-1-2-14(15(22)9-13)20-18(16-3-6-23-11-24-16)19(25-26-20)12-4-7-27(8-5-12)17(29)10-28/h1-3,6,9,11-12,28H,4-5,7-8,10H2,(H,25,26)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. CRYSTALLINE FORM OF 2-&lcub 4-‘3-(4-CHLORO-2-FLUOROPHENYL)-4-PYRIMIDIN-4-YL-1H-PYRAZOL-5-YL!PIPERIDIN-1-YL&rcub -2-OXOETHANOL. WO/2005/061486 A1

Products are for research use only. Not for human use.