详情描述
p38α inhibitor 1 is a p38α inhibitor extracted from patent WO 2008076265 A1.
Product information
CAS Number: 1034189-82-6
Molecular Weight: 416.46
Formula: C22H26F2N4O2
Chemical Name: 5-(2, 4-difluorophenoxy)-N-[2-(dimethylamino)ethyl]-1-(2-methylpropyl)-1H-indazole-6-carboxamide
Smiles: CN(C)CCNC(=O)C1=CC2=C(C=NN2CC(C)C)C=C1OC1=CC=C(F)C=C1F
InChiKey: IFGWYHGYNVGVRB-UHFFFAOYSA-N
InChi: InChI=1S/C22H26F2N4O2/c1-14(2)13-28-19-11-17(22(29)25-7-8-27(3)4)21(9-15(19)12-26-28)30-20-6-5-16(23)10-18(20)24/h5-6,9-12,14H,7-8,13H2,1-4H3,(H,25,29)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : ≥ 125 mg/mL (300.15 mM)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥360 days if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- Baker W, et al. Monophosphates as mutual prodrugs of anti-inflammatory signal transduction modulators (aistm's) and β-agonists for the treatment of pulmonary inflammation and bronchoconstriction. WO 2008076265 A1.
Products are for research use only. Not for human use.