EGFR Protein Tyrosine Kinase Substrate

EGFR Protein Tyrosine Kinase Substrate is a EGFR protein tyrosine kinase substrate.

Product information

CAS Number: 945830-38-6

Molecular Weight: 1076.16

Formula: C48H73N11O17

Chemical Name: (3S, 6S, 9S, 12S, 15S, 16S)-15-((S)-2-((S)-5-amino-1-((S)-4-amino-1-carboxy-4-oxobutylamino)-1, 5-dioxopentan-2-ylcarbamoyl)pyrrolidine-1-carbonyl)-3-((S)-2-aminopropanamido)-6-(2-carboxyethyl)-9-(4-hydroxybenzyl)-12-isobutyl-16-methyl-4, 7, 10, 13-tetraoxo-5, 8, 11, 14-tetraazaoctadecan-1-oic acid

Smiles: CC(C)C[C@H](NC(=O)[C@H](CC1=CC=C(O)C=C1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](C)N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(O)=O

InChiKey: LQRUFPWSECMCHG-YBFBXAKBSA-N

InChi: InChI=1S/C48H73N11O17/c1-6-24(4)39(47(74)59-19-7-8-34(59)46(73)53-28(13-16-35(50)61)41(68)54-30(48(75)76)14-17-36(51)62)58-45(72)31(20-23(2)3)56-43(70)32(21-26-9-11-27(60)12-10-26)57-42(69)29(15-18-37(63)64)52-44(71)33(22-38(65)66)55-40(67)25(5)49/h9-12,23-25,28-34,39,60H,6-8,13-22,49H2,1-5H3,(H2,50,61)(H2,51,62)(H,52,71)(H,53,73)(H,54,68)(H,55,67)(H,56,70)(H,57,69)(H,58,72)(H,63,64)(H,65,66)(H,75,76)/t24-,25-,28-,29-,30-,31-,32-,33-,34-,39-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Wang Y, Liu M, Gao J. Enhanced receptor binding of SARS-CoV-2 through networks of hydrogen-bonding and hydrophobic interactions. Proc Natl Acad Sci U S A. 2020 Jun 23;117(25):13967-13974.

Products are for research use only. Not for human use.