Seco-Duocarmycin TM


Catalog No. Size 价格库存数量
S0906-2 2mg solid ¥665
S0906-10 10mg solid ¥2,660


Seco-Duocarmycin TM is a DNA alkylator agent belonging to Duocarmycins family that inhibits DNA synthesis. Seco-Duocarmycin TM is a cytotoxic agent, used as the cytotoxic component in antibody-drug conjugates (ADC).

Product information

CAS Number: 236102-87-7

Molecular Weight: 448.47

Formula: C25H24N2O6

Chemical Name: (1S)-1-(hydroxymethyl)-3-(5, 6, 7-trimethoxy-1H-indole-2-carbonyl)-1H, 2H, 3H-benzo[e]indol-5-ol

Smiles: COC1=C(OC)C2NC(=CC=2C=C1OC)C(=O)N1C[C@@H](CO)C2=C1C=C(O)C1=CC=CC=C21


InChi: InChI=1S/C25H24N2O6/c1-31-20-9-13-8-17(26-22(13)24(33-3)23(20)32-2)25(30)27-11-14(12-28)21-16-7-5-4-6-15(16)19(29)10-18(21)27/h4-10,14,26,28-29H,11-12H2,1-3H3/t14-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200


  1. Gieseg MA, et al. Comparison of the patterns of DNA alkylation by phenol and amino seco-CBI-TMI compounds: use of a PCR method for the facile preparation of single end-labelled double-stranded DNA. Anticancer Drug Des. 1999 Feb;14(1):77-84.

Products are for research use only. Not for human use.


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