NH2-PEG2-CH2-Boc

NH2-PEG2-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 1948273-09-3

Molecular Weight: 233.30

Formula: C11H23NO4

Chemical Name: tert-butyl 2-[3-(2-aminoethoxy)propoxy]acetate

Smiles: CC(C)(C)OC(=O)COCCCOCCN

InChiKey: JRZMKPMLVHFHOR-UHFFFAOYSA-N

InChi: InChI=1S/C11H23NO4/c1-11(2,3)16-10(13)9-15-7-4-6-14-8-5-12/h4-9,12H2,1-3H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 150 mg/mL (642.95 mM; Need ultrasonic) H2O : 20 mg/mL (85.73 mM; Need ultrasonic)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Products are for research use only. Not for human use.