详情描述
Gallein is a Gβγ subunit signalling inhibitor which has been shown to inhibit metastatic spread of tumour cells expressing OR51E2 and exposed to its odorant ligand.
Product information
CAS Number: 2103-64-2
Molecular Weight: 364.31
Formula: C20H12O7
Chemical Name: 3', 4', 5', 6'-Tetrahydroxyspiro(isobenzofuran-1(3H), 9'-(9H)xanthene)-3-one
Smiles: OC1C=CC2=C(OC3C(=CC=C(O)C=3O)C32OC(=O)C2=CC=CC=C32)C=1O
InChiKey: PHLYOKFVXIVOJC-UHFFFAOYSA-N
InChi: InChI=1S/C20H12O7/c21-13-7-5-11-17(15(13)23)26-18-12(6-8-14(22)16(18)24)20(11)10-4-2-1-3-9(10)19(25)27-20/h1-8,21-24H
Technical Data
Appearance: Chemical Structure
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 33.33 mg/mL (91.49 mM; ultrasonic and warming and heat to 80°C)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥360 days if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- Sanz G, et al. Gallein, a Gβγ subunit signalling inhibitor, inhibits metastatic spread of tumour cells expressing OR51E2 and exposed to its odorant ligand. BMC Res Notes. 2017 Oct 30;10(1):541.
- Lillie RD, et al. Hematoxylin substitutes: gallein as a biological stain. Stain Technol. 1974 Nov;49(6):339-46.
Products are for research use only. Not for human use.