详情描述
Olprinone (INN) is a cardiotonic agent and a specific phosphodiesterase (PDE)-III inhibitor. It has been marketed in Japan since 1996. Olprinone attenuates excessive shear stress through up-regulation of endothelial nitric oxide synthase in a rat excessive hepatectomy model. Olprinone reduces the development of multiple organ dysfunction syndrome in mice.
Product information
CAS Number: 106730-54-5
Molecular Weight: 250.26
Formula: C14H10N4O
Chemical Name: 5-{imidazo[1,2-a]pyridin-6-yl}-6-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile
Smiles: CC1NC(=O)C(=CC=1C1=CN2C=CN=C2C=C1)C#N
InChiKey: JPAWFIIYTJQOKW-UHFFFAOYSA-N
InChi: InChI=1S/C14H10N4O/c1-9-12(6-11(7-15)14(19)17-9)10-2-3-13-16-4-5-18(13)8-10/h2-6,8H,1H3,(H,17,19)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥360 days if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.