Catalog No. Size 价格库存数量
S1799-2 Solid 2 mg ¥3,760
售罄
不可用
S1799-10 Solid 10 mg ¥15,040
售罄
不可用

详情描述

Trabectedin (also known as ecteinascidin 743 or ET-743, trade name Yondelis) is an antitumor chemotherapy drug sold by Pharma Mar S.A. and Johnson and Johnson under the brand name Yondelis. It is approved for use in Europe, Russia, and South Korea for the treatment of advanced soft-tissue sarcoma. It is also undergoing clinical trials for the treatment of breast, prostate, and paediatric sarcomas. The European Commission and the U.S. Food and Drug Administration (FDA) have granted orphan drug status to trabectedin for soft-tissue sarcomas and ovarian cancer.

Product information

CAS Number: 114899-77-3

Molecular Weight: 761.84

Formula: C39H43N3O11S

Chemical Name: (1R,2R,3R,11S,12S,14R,26R)-5,6',12-trihydroxy-6,7'-dimethoxy-7,21,30-trimethyl-27-oxo-3',4'-dihydro-2'H-17,19,28-trioxa-24-thia-13,30-diazaspiro[heptacyclo[12.9.6.1³,¹¹.0²,¹³.0⁴,⁹.0¹⁵,²³.0¹⁶,²⁰]triacontane-26,1'-isoquinoline]-4(9),5,7,15,20,22-hexaen-22-yl acetate

Smiles: CN1[C@H]2CC3=CC(C)=C(OC)C(O)=C3[C@@H]1[C@@H]1[C@@H]3SC[C@]4(NCCC5=CC(O)=C(C=C45)OC)C(=O)OC[C@@H](C4=C3C(OC(C)=O)=C(C)C3OCOC=34)N1[C@H]2O

InChiKey: PKVRCIRHQMSYJX-AIFWHQITSA-N

InChi: InChI=1S/C39H43N3O11S/c1-16-9-20-10-22-37(46)42-23-13-50-38(47)39(21-12-25(48-5)24(44)11-19(21)7-8-40-39)14-54-36(30(42)29(41(22)4)26(20)31(45)32(16)49-6)28-27(23)35-34(51-15-52-35)17(2)33(28)53-18(3)43/h9,11-12,22-23,29-30,36-37,40,44-46H,7-8,10,13-15H2,1-6H3/t22-,23-,29+,30+,36+,37-,39+/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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