详情描述
Oseltamivir Free Base is an acetamido cyclohexene that is a structural homolog of SIALIC ACID and inhibits NEURAMINIDASE. It is used in Influenza treatment
Product information
CAS Number: 196618-13-0
Molecular Weight: 312.40
Formula: C16H28N2O4
Synonym:
GS 4104
GOP-A-Flu
Tamiflu-Free
Tamvir
Chemical Name: ethyl (3R,4R,5S)-5-amino-4-acetamido-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylate
Smiles: CC(=O)N[C@@H]1[C@@H](N)CC(=C[C@H]1OC(CC)CC)C(=O)OCC
InChiKey: VSZGPKBBMSAYNT-RRFJBIMHSA-N
InChi: InChI=1S/C16H28N2O4/c1-5-12(6-2)22-14-9-11(16(20)21-7-3)8-13(17)15(14)18-10(4)19/h9,12-15H,5-8,17H2,1-4H3,(H,18,19)/t13-,14+,15+/m0/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: To be determined
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
References:
- Tagarro A, Cruz-Cañete M, Otheo E, Launes C, Couceiro JA, Pérez C, Alfayate S; en nombre del Grupo de trabajo de Infecciones Respiratorias de la Sociedad Española de Infectología Pediátrica (SEIP); Miembros del Grupo de Trabajo de Infecciones Respiratorias de la SEIP que han participado en la revisión del manuscrito. Oseltamivir para el tratamiento de la gripe en niños y adolescentes [Oseltamivir for the treatment of influenza in children and adolescents]. An Pediatr (Barc). 2019 May;90(5):317.e1-317.e8. Spanish.
- Ono H. [Hypothermic Action of Oseltamivir Not Dependent on Its Anti-influenza Virus Action]. Yakugaku Zasshi. 2019;139(5):767-781. Japanese.
- Lee J, Park JH, Jwa H, Kim YH. Comparison of Efficacy of Intravenous Peramivir and Oral Oseltamivir for the Treatment of Influenza: Systematic Review and Meta-Analysis. Yonsei Med J. 2017 Jul;58(4):778-785.
Products are for research use only. Not for human use.