Catalog No. Size 价格库存数量
S2280-2 Solid 2 mg ¥80
售罄
不可用
S2280-10 Solid 10 mg ¥240
售罄
不可用

详情描述

Niraparib, also known as MK4827, is an orally active, potent and selective poly(ADP-Ribose) polymerase (PARP) inhibitor that radiosensitizes human lung and breast cancer cells. Niraparib inhibits PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM respectively. Niraparib is currently in Phase 3 clinical trials for ovarian cancer and BRCA+ breast cancer.

Product information

CAS Number: 1038915-60-4

Molecular Weight: 320.39

Formula: C19H20N4O

Chemical Name: 2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide

Smiles: NC(=O)C1=CC=CC2=CN(N=C21)C1C=CC(=CC=1)[C@H]1CNCCC1

InChiKey: PCHKPVIQAHNQLW-CQSZACIVSA-N

InChi: InChI=1S/C19H20N4O/c20-19(24)17-5-1-3-15-12-23(22-18(15)17)16-8-6-13(7-9-16)14-4-2-10-21-11-14/h1,3,5-9,12,14,21H,2,4,10-11H2,(H2,20,24)/t14-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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